Chronic uterine infections, often referred to as chronic endometritis, are persistent inflammatory conditions caused by various types of bacteria, viruses, or other microorganisms. These conditions can lead to a range of symptoms and often pose a challenge for treatment. In this article, we will delve deeper into the causes, symptoms, and treatment options for chronic uterine infections.


Chronic uterine infections can be attributed to a variety of causes. Most commonly, they are the result of an untreated or inadequately treated acute infection. These can include sexually transmitted infections (STIs) such as Chlamydia or gonorrhea, bacteria that naturally occur in the vaginal area, or specific conditions like tuberculosis. Other risk factors include a weakened immune system, multiple sexual partners, invasive gynecological procedures, and certain chronic diseases.


Chronic endometritis often presents as asymptomatic or with non-specific symptoms, making the diagnosis challenging. Possible symptoms can include lower abdominal pain, irregular menstruation, unusual vaginal discharge, fever, malaise, and infertility.

Diagnostic Procedures

The diagnosis of a chronic uterine infection can be complex and typically requires a thorough medical history, physical examination, and specialized tests. Histopathology, which includes the study of tissues under a microscope, is the gold-standard procedure for diagnosis. Additionally, various imaging procedures such as ultrasound, CT, or MRI can be helpful.


The treatment of a chronic uterine infection depends on the specific cause of the infection. In most cases, treatment involves a prolonged course of antibiotics. If the infection is traced back to an STI, both partners should be treated to prevent re-infection. In severe cases or when the infection does not respond to treatment, surgical intervention may be necessary.


Chronic uterine infections can have significant health impacts and lead to infertility and other serious complications. Early detection and treatment are therefore critical. Patients are encouraged to seek medical professionals for persistent or recurring symptoms. Future research in this area should focus on improving diagnostic methods and developing more effective treatment strategies.

Source: This article was written based on the current state of scientific and clinical practice as of the date of publication (August 2023).